Sách chuyên ngành Y Dược: Autoimmune Diseases of the Skin: Pathogenesis, Diagnosis, Management – 3rd Edition (Bệnh tự miễn của da - Bản 3)

MICHAEL HERTL

AUTOIMMUNE DISEASES OF THE SKIN: PATHOGENESIS, DIAGNOSIS, MANAGEMENT - THIRD EDITION

(BỆNH TỰ MIỄN CỦA DA - BẢN 3)

PUBLISHER: SPRINGERWIENNEWYORK (2011)

THÔNG TIN CHUNG:

Tiêu đề: Autoimmune Diseases of the Skin: Pathogenesis, Diagnosis, Management – 3rd Edition (tạm dịch: Bệnh tự miễn của da - Bản 3).

Tác giả: Michael Hertl.

NXB: SpringerWienNewYork (2011).

Thông số: 617 trang - 19 chương chính.

Thế giới đang phải đối mặt với tỷ lệ mắc các bệnh tự miễn ngày càng tăng. Đây là một trong những nhóm bệnh lý gây tử vong hàng đầu, làm giảm tuổi thọ trung bình 15 năm, với chi phí điều trị hàng năm ước tính trên 120 tỷ đô-la Mỹ. Cuốn sách này sẽ cung cấp cho quý độc giả những kiến thức tiên tiến nhất về bệnh tự miễn như triệu chứng bệnh lý, phương pháp chẩn đoán và điều trị. Sách bản đẹp, mục lục tự động, minh họa bằng hình ảnh trực quan, hy vọng sẽ đem đến cho độc giả thêm nhiều kiến thức quý báu!

INTRODUCTION (GIỚI THIỆU):

Based on recent advances in the understanding of the immunological pathogenesis of many chronic inflammatory disorders there is increasing evidence that several of them are characterized and potentially mediated by autoimmune phenomena. Classical examples are rheumatoid arthritis, myasthenia gravis, pemphigus vulgaris, lupus erythematosus and multiple sclerosis. Others, such as psoriasis vulgaris, some less well-characterized collagen vascular disorders, vasculitides and a subtype of chronic urticaria have a more or less pro-nounced autoimmune background that has to be considered in the overall management of these disorders. A significant portion of autoimmune diseases precipitate primarily or sec-ondarily at the skin. Understanding the cutaneous symptoms may be therefore crucial for the diagnosis, classification and therapeutic management of organ-specific and systemic disorders that require special attention by the physician.

This book is set out to present the most recent scientific and clinically relevant state-of-the-art-knowledge on the broad spectrum of autoimmune disorders affecting the skin. It is meant to provide the most recent information on these disorders for clinicians as well as practicioners in dermatology, medicine, rheumatology, ENT, pediatrics, ophthalmol-ogy, orthopedics etc and for basic scientists interested in human autoimmunity. Each book chapter dealing with a distinct cutaneous autoimmmune disorder consists of an introduc-tion focusing on the state of knowledge regarding pathogenesis and epidemiology followed by a practical guide how to identify and handle the particular disorder(s). Special attention is paid to genuine cutaneous autoimmune disorders such as autoimmune bullous skin dis-orders including pemphigus, pemphigoid and epidermolysis bullosa acquisita. These dis-orders can be considered as paradigms of organ-specific autoimmune disorders because autoantigens and autoantibody-mediated pathogenesis are well-characterized.

Major progress has been made in the diagnosis and classification of collagen vascular disorders such as systemic sclerosis, lupus erythematosus, dermatomyositis and overlap syndromes. These advances have provided the basis for more specific therapeutic interven-tions. Recent pathogenetic findings in psoriasis, lichen planus and chronic urticaria have led to novel therapeutic concepts that will replace the “classical” symptomatic treatments that have been established for decades. One striking example is the therapeutic effect of bi-ologics in severe psoriasis vulgaris and psoriatic arthritis and the modulatory effect of high dose immunoglobulins in dermatomyositis and severe vasculitides. In addition to the book chapters on distinct clinical cutaneous disorders, the introductory chapter explains basic immunological principles leading to autoimmunity and the final chapter gives an over-view of the mode of action of novel immunomodulatory drugs. The present book which is edited by my co-worker Dr. Michael Hertl is set out to combine major scientific advances in the understanding of autoimmunity with the clinical presentation and management of these disorders. I am convinced that the book constitutes a very successful effort to provide a handbook for those who are scientifically or clinically interested in autoimmune disor-ders of the skin. I wish the editor and the authors success with this endeavor.

TABLE OF CONTENTS (MỤC LỤC):

1 Pathogenesis of Autoimmune Diseases

Martin Röcken and Tilo Biedermann

2 Autoantibody Detection Using Indirect Immunoluorescenceon HEp-2 Cells

Philipp von Landenberg 3 Autoimmune Bullous Skin Disorders

3.1 Pemphigus

Michael Hertl and Rüdiger Eming

3.2 Bullous Pemphigoid: Clinical Features, Diagnostic Markers, and Immunopathogenic Mechanisms

Giovanni Di Zenzo, Emmanuel Laitte, Giovanna Zambruno and

Luca Borradori

3.3 Dermatitis Herpetiformis Duhring

Christian Rose and Detlef Zillikens

3.4 Epidermolysis Bullosa Acquisita

Gene Kim, Mei Chen, Dafna Hallel-Halevy, and David T. Woodley

4 Scleroderma

4.1 Localized Scleroderma

Cristián Vera Kellet, Catherine H. Orteu, and Jan P. Dutz

4.2 Progressive Systemic Scleroderm

Nicolas Hunzelmann and homas Krieg

5 Lupus Erythematosus

5.1 Chronic Cutaneous Lupus Erythematosus

Michael Sticherling

5.2 Subacute Cutaneous and Systemic Lupus Erythematosus

Donna M. Pellowski, Jane E. Kihslinger, and Richard D. Sontheimer

6 Dermatomyositis

Ruth Ann Vleugels and Jefrey P. Callen

7 Mixed Connective Tissue Disease

Reiji Kasukawa

8 Sjögren’s Syndrome

Robert I. Fox and Carla M. Fox

9 Psoriasis Vulgaris and Arthopathica

Arnd Jacobi and Jörg Christoph Prinz

10 Chronic Urticaria as an Autoimmune Disease

Clive Grattan, Michihiro Hide, and Malcolm W. Greaves

11 Lichen Planus, Lichenoid Eruptions and Cutaneous Grat-Versus-HostReaction

Miklós Simon Jr

12 Small Vessel Vasculitides

Peter Lamprecht and Wolfgang L. Gross

13 Skin Manifestations of Rheumatic Diseases

Camille Francès and Nicolas Kluger

14 Vitiligo

Karin U. Schallreuter

15 Alopecia Areata

Pia Freyschmidt-Paul, Kevin McElwee, and Rolf Hofmann

16 Autoimmune Phenomena in Atopic Dermatitis

Caroline Bussmann and Natalija Novak

17 Eosinophils in Autoimmune Bullous Diseases

Dagmar Simon and Hans-Uwe Simon

18 Paraneoplastic Syndromes of the Skin

Peter Fritsch

19 Targeted herapies in Autoimmune and Inlammatory Skin Disorders

Rüdiger Eming and Ingo H. Tarner

Subject Index

AUTOIMMUNE DISEASES OF THE SKIN: PATHOGENESIS, DIAGNOSIS, MANAGEMENT - THIRD EDITION

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